UV Skin-protection from Vitamin C and E Combination
Our Sun emits UV radiation, which causes acute adverse effects like sunburn, as well as chronic conditions like photoageing or malignant skin tumors. UV rays induce tissues to produce harmful substances, the inhibition of which may reduce skin damage. Antioxidants such as ascorbic acid (Vitamin C) and d-α-tocopherol (Vitamin E) have been found to be photoprotective in some studies, whereas their combination can reduce the sunburn reaction, which may indicate a consequent reduced risk for later UV-induced skin damage.
[Study details] from the Journal of the American Academy of Dermatology
Photoprotective Effects of Vitamin E
The antioxidant vitamin E (d-α-tocopherol) may protect both animal and plant cell membranes from light-induced damage. The various biochemical and biophysical modes of protection are considered, and an examination is made of the evidence that vitamin E plays an important prophylactic role against a number of serious light-induced diseases and conditions of the eye and skin that are mediated (i.e. brought about) by photooxidative damage to cell membranes.
[Study details] from the American Society of Photobiology
Supplements for Healthy Skin
Aging and the sun take a toll on our skin. Increasingly, people are adding antioxidants to their skin care routine, with the goal of helping protect skin from the inside out. Vitamins C and E and selenium are antioxidants that may help protect skin from sun damage while improving skin health and quality.
[Full article] from WebMD
Skin-protective effect from a Good Diet
Grab some sun block, a hat and protective clothing, then also think about the food you eat to help guard against skin cancer. That’s the advice from Kansas State University nutrition educator Mary Meck Higgins, who says many common foods can help protect skin against damage caused by normal exposure to the sun.
[Full article] from the Kansas State University Research and Extension
Photoprotective Effects of Almonds
Almonds are a great source of vitamin E and other antioxidants that nourish the skin and reduce signs of aging. Research finds that almonds nutrition contains high concentrations of catechin, epicatechin and flavonol antioxidants, including quercetin, kaempferol and isorhamnetin — compounds that fight skin cancer and damage by reversing oxidative stress from a poor diet, pollution and UV light exposure. Flavonoids from almond skins are bioavailable and act synergistically with vitamins C and E to enhance hamster and human LDL resistance to oxidation.
[Study details] from the U.S. Department of Agriculture Human Nutrition Research Center on Aging
Natural ways to Prevent Sunburn
Many of us shun the sun because we are afraid of skin damage overexposure can cause. But sunburn, photoageing and skin cancer are not inevitable if you adopt certain common sense measures, such as eating the right diet, including significant supplements of the right vitamins and nutrients.
[Full article] from Healthy.net
Skin Care Vitamins and Antioxidants
Research has found that vitamins C and E, as well as selenium, can help protect the skin against sun damage and skin cancer, and they may actually reverse some of the discoloration and wrinkles associated with aging. These antioxidants work by speeding up the skin’s natural repair systems and by directly inhibiting further damage, says Karen E. Burke, MD, PhD, of the Mount Sinai School of Medicine’s department of dermatology.
[Full article] from WebMD
Can Vitamins Protect Skin from the Sun?
In some cases, vitamins C and E have been credited with preventing sunburns, and they can also make the effects of the sun less severe. The key is combining them. Separately, vitamins C and E aren’t nearly as effective as they are when taken together. These vitamins can’t fully replace sunscreen, but they can help prevent, and even repair, some sun damage.
[Full article] from HowStuffWorks.com
Vitamin E and C Synergistic Sunburn Suppression
This clinical trial studied whether oral supplementation with D-alpha-tocopherol (Vitamin E), L-ascorbic acid (Vitamin C), or their combination influenced the solar radiation induced skin inflammation in healthy volunteers. The trial found evidence that a combination of vitamins E and C acts synergistically in suppression of the sunburn reaction.
[Study details] from J.W. Goethe University Medical School Dept of Dermatology
Lots of Vitamin C is Good for the Body
Vitamin C is one of the safest and most effective nutrients, delivering protection against immune system deficiencies, cardiovascular disease, prenatal health problems, eye disease, and even skin wrinkling. A recent study looked at over 100 studies over 10 years, revealing a growing list of its benefits. “But,” notes a study researcher, “the ideal dosage may be higher than the recommended dietary allowance.”
[Full article] from WebMD
Vitamin E and Skin Health
Vitamin E is an integral part of the skin’s antioxidant defenses, primarily providing protection against UV radiation and other free radicals that may come in contact with the epidermis. Oral supplementation with only vitamin E may not provide adequate protection for the skin, and co-supplementation of vitamin E and vitamin C may be warranted to effectively increase the photoprotection of skin through the diet.
[Study details] from Oregon State University’s Micronutrient Research for Optimum Health
Sunscreen with antioxidants provides better UVA/UVB protection
TRUE. While they aren’t active sunscreen ingredients, antioxidants are great SPF supplements. Sunscreen alone does not block all of the damaging rays from the sun — even an SPF of 50 blocks out only 98% of UV rays. “Antioxidants are a good way to catch the UV radiation that ‘sneaks’ past the sunscreen,” Gohara says. Sunscreens infused with antioxidants, such as skin-loving green tea extract or polyphenols from tomatoes and berries, are proven to reduce the formation of free radicals (small chemical particles that wreak havoc on skin and can cause skin cancer) in the presence of UV light.
[Full article] from WedMD
Antioxidants and the response of skin to oxidative stress: Vitamin E as a key indicator
As the outermost barrier of the body, the skin is directly and frequently exposed to a prooxidative environment, including solar UVA and UVB radiation, and air pollution. The skin is equipped with an elaborate system of antioxidant substances and enzymes that includes a network of redox active antioxidants. Among these, vitamin E has been identified as the predominant antioxidant. Skin exposure to UV and ozone alone and in combination resulted in a significant potentiation of the UV-induced vitamin E depletion. Oxidants and antioxidants play an important role in maintaining a balance between free radicals produced by metabolism or derived from environmental sources.
[Study details] from Skin Pharmacology and Applied Skin Physiology
Nutritional skin care: health effects of micronutrients and fatty acids
Modern nutritional science is developing new insights into the relation between food intake and health, and effects of food ingredients may prove to be biologically relevant for optimal skin condition. The nutrients of focus were vitamins, carotenoids, and polyunsaturated fatty acids. Supplementation with these nutrients was shown to provide protection against ultraviolet light, although the sun-protection factor was relatively small compared with that of topical sunscreens. An increase in delayed-type hypersensitivity skin responses after supplementation with nutrients has proven beneficial.
[Full article] from American Journal of Clinical Nutrition
The Role of Antioxidants in Skin Cancer Prevention and Treatment
Skin DNA molecules are constantly “bombarded” by ROS originating from endogenous processes as well as from environmental agents and from radiation sources. Antioxidants might act by quenching free radicals and by enhancing the DNA enzyme repair systems through a posttranscriptional gene regulation of transcription factors. The repair capacity of human skin cells therefore directly relates to the probability of initiation of the carcinogenesis process and eventually tumor formation. Evidence is accumulating that dietary changes and special nutrients may help to reduce oxidative stress and free radical formation and thereby slow down the skin damage process. Exogenous antioxidants like vitamins C and E and many others cannot be synthesized by the human body and must be taken up by the diet.
[Study details] from Oxidative Medicine and Cellular Longevity
Skin Photoaging and the Role of Antioxidants in Its Prevention
Photoaging of the skin depends primarily on the degree of ultraviolet radiation (UVR) and on an amount of melanin in the skin (skin phototype). In addition to direct or indirect DNA damage, UVR activates cell surface receptors of keratinocytes and fibroblasts in the skin, which leads to a breakdown of collagen in the extracellular matrix and a shutdown of new collagen synthesis. It seems that skin’s antioxidative defence is also influenced by vitamins and nutritive factors and that combination of different antioxidants simultaneously provides synergistic effect.
[Full article] from ISRN Dermatology
Effectiveness of antioxidants (Vitamin C and E) with and without sunscreens as topical photoprotectants.
Two of the best known anti-oxidants are vitamins C and E, both of which have been shown to be somewhat effective in different models of photo damage. A combination of both vitamins E and C provided very good protection from a UVB insult, the bulk of the protection attributable to vitamin E. However, vitamin C is significantly better than vitamin E at protecting against a UVA-mediated phototoxic insult in this animal model, while the combination is only slightly more effective than vitamin C alone. When vitamin C or a combination of vitamin C and E is formulated with a commercial UVA sunscreen (oxybenzone), an apparently greater than additive protection is noted against the phototoxic damage. These results confirm the utility of anti-oxidants as photoprotectants but suggest the importance of combining the compounds with known sunscreens to maximize photoprotection.
[Study details] from Acta Derm Venereol
Nutritional Protection Against Skin Damage from Sunlight
The concept of systemic photoprotection by dietary means is gaining momentum. Skin is continuously exposed to ultraviolet (UV) radiation, the major cause of skin disorders such as sunburn, photodamage, and nonmelanoma skin cancer. Most of the erythemal annual UV dose is encountered under nonvacation conditions, when no sunscreen is applied. In the absence of topically added compounds, skin protection depends solely on endogenous defense. Micronutrients can act as UV absorbers, as antioxidants, or can modulate signaling pathways elicited upon UV exposure. UV-induced erythema is a suitable parameter to assess photoprotection. Dietary protection is provided by carotenoids, tocopherols, ascorbate, flavonoids, or n-3 fatty acids, contributing to maintenance resistance as part of lifelong protection.
[Full article] from Annual Review of Nutrition
Ultraviolet B-induced DNA damage in human epidermis is modified by the antioxidants vitamin C and vitamin E.
DNA damage caused by ultraviolet (UV) irradiation is considered the main etiologic factor contributing to the development of skin cancer. Systemic or topical application of antioxidants has been suggested as a protective measure against UV-induced skin damage. We investigated the effect of long-term oral administration of a combination of the antioxidants ascorbic acid (vitamin C) and D-alpha-tocopherol (vitamin E) in human volunteers on UVB-induced epidermal damage. The intake of vitamins C and E for a period of 3 mo significantly reduced the sunburn reaction to UVB irradiation. Detection of thymine dimers in the skin using a specific antibody revealed a significant increase of this type of DNA damage following UVB exposure. After 3 mo of antioxidant administration, significantly less thymine dimers were induced by the UVB challenge, suggesting that antioxidant treatment protected against DNA damage.
[Study details] from Journal of Investigative Dermatology
The Health Effects of Vitamin C Supplementation: a Review
A comprehensive review of the literature indicates that populations with long-term consumption of higher than RDA levels of vitamin C (> or = 60 mg/day) from foods and/or supplements have reduced risks of cancer at several sites, cardiovascular disease, and cataracts. The safety of higher than RDA intakes of vitamin C is confirmed in eight placebo-controlled, double-blind studies and six non-placebo clinical trials in which up to 10,000 mg of vitamin C was consumed daily for up to 3 years. There are no clinical data which suggest that vitamin C’s enhancement of non-heme iron absorption in individuals with low iron status could be a critical factor in the possible increased risk of heterozygous hemochromatosis-related cardiovascular disease. In fact, the cumulative data do not confirm that iron status is related to risk of cardiovascular disease. Moreover, higher than RDA intakes of vitamin C have been associated with several indices of lowered cardiovascular disease risk including increases in HDL, and decreases in LDL oxidation, blood pressure and cardiovascular mortality.
[Study details] from Journal of the American College of Nutrition
Skin and Antioxidants
It is estimated that total sun exposure occurs non-intentionally in three quarters of our lifetimes. Our skin is exposed to majority of UV radiation during outdoor activities, e.g. walking, practicing sports, running, hiking, etc. and not when we are intentionally exposed to the sun on the beach. We rarely use sunscreens during those activities, or at least not as much and as regular as we should and are commonly prone to acute and chronic sun damage of the skin. The only protection of our skin is endogenous (synthesis of melanin and enzymatic antioxidants) and exogenous (antioxidants, which we consume from the food, like vitamins A, C, E, etc.). UV-induced photoaging of the skin becomes clinically evident with age, when endogenous antioxidative mechanisms and repair processes are not effective any more and actinic damage to the skin prevails. At this point it would be reasonable to ingest additional antioxidants and/or to apply them on the skin in topical preparations.
[Study details] from Journal of Cosmetic and Laser Therapy
Nutritional approach to sun protection: a suggested complement to external strategies
The increasing incidence of skin cancer despite the use of externally applied sun protection strategies, alongside research showing that nutrients reduce photo-oxidative damage, suggest nutritional approaches could play a beneficial role in skin cancer prevention. Penetrating photo-oxidative ultraviolet A radiation reduces skin and blood antioxidants and damages cell components, including DNA. Dietary antioxidant vitamins, minerals, and phytochemicals in addition to n-3 polyunsaturated fatty acids, n-9 monounsaturated fatty acids, and low pro-inflammatory n-6 polyunsaturated fatty acids, have demonstrated protective properties. The presence of these elements in the traditional Greek-style Mediterranean diet may have contributed to the low rates of melanoma in the Mediterranean region despite high levels of solar radiation. This suggests a potentially relevant model for studying dietary/nutritional supplementation for lifelong internal support of sun-protection mechanisms, which could complement external strategies.
[Study details] from Nutrition Reviews
Human skin condition and its associations with nutrient concentrations in serum and diet
Nutritional factors exert promising actions on the skin, but only scant information is available on the modulating effects of physiologic concentrations of nutrients on the skin condition of humans. After adjustment for potential confounders, including sex, age, and smoking, statistically significant associations were shown in the total population between serum vitamin A and skin sebum content and surface pH and between the dietary intake of total fat, saturated fat, monounsaturated fat, and skin hydration. Monounsaturated fat intake was also associated with surface pH. Associations between serum β-cryptoxanthin and skin hydration and between surface pH and fluid and calcium intakes were observed in men only. Several associations between nutrients in serum and diet and skin condition were observed, indicating that changes in baseline nutritional status may affect skin condition.
[Study details] from American Society for Clinical Nutrition
Direct observation of a free radical interaction between vitamin E and vitamin C
Vitamin E (α-tocopherol) and vitamin C (ascorbic acid) react rapidly with organic free radicals, and it is widely accepted that the antioxidant properties of these compounds are responsible in part for their biological activity1–5. Tissue vitamin C levels are often considerably greater than those of vitamin E, for example in liver the values are approximately 2 mM and 0.02 mM, respectively. Nevertheless, vitamin E is considerably more lipophilic than vitamin C, and in biomembranes has been found to be the more potent antioxidant, particularly with respect to lipid peroxidation; penetration to a precise site in the membrane may be an important feature of the protection against highly reactive radicals6. Tappel has suggested that the two vitamins act synergistically, vitamin E acting as the primary antioxidant and the resulting vitamin E radical then reacting with vitamin C to regenerate vitamin E7. We now report direct observation of this interaction, which we feel may be an important feature in the maintenance of vitamin E levels in tissues.
[Study details] from Nature
Healthy Foods, Healthy Skin
New research suggests some foods have the power to guard skin from the damage caused by the sun’s UV radiation. While a salad is no substitute for sunblock, these healthy foods could add inner protection against sunburn and wrinkles at the cellular level.
[Full article] from Reader’s Digest
New Role Of Vitamin C In Skin Protection
Researchers at the University of Leicester and Institute for Molecular and Cellular Biology in Portugal studied new protective properties of vitamin C in cells from the human skin, which could lead to better skin regeneration.
[Study details] from Science Daily
9 Sun-protective Foods
You may be surprised to learn that many common foods offer some protection to your skin from the potentially damaging rays of the sun, from the inside out. This SPF or sun protective factor aspect of foods has to do with the presence of certain antioxidant compounds. Plants produce antioxidants within their own tissues to protect their own cells from premature destruction, due to exposure to heat, light, air, moisture and time. When we consume many of these plant-derived antioxidants, these natural agents provide protection to the cells of our bodies, including skin cells. By eating certain foods, especially those that are brightly colored, you can actually help to reduce damage to your skin caused by exposure to UVA and UVB rays from sunlight. Let’s consider some of the better sun protective foods.
[Full article and video] from Fox News
6 Food Groups That Will Protect You From the Sun
Slathering on sunscreen is never enjoyable. Does that stuff ever blend in completely? While it’s always important to spread on at least a thin layer of sunblock, some other super powerful UV-blockers are hiding right in the produce aisle. Meet the double-duty foods that have been shown to increase the skin’s ability to protect against UV damage. Oh, and they’re part of a healthy diet, too. Their sunblocking secret: Antioxidants. These compounds help fight free radicals, a nasty set of atoms or molecules that contribute to annoying problems like premature aging and can be a product of unprotected sun exposure. Free radicals prowl the body, stealing electrons from healthy cells (in this case, in the skin). Antioxidants are a person’s mini-martyrs, running around the body and giving up their extra electrons to free radicals so they stop pestering the healthy cells.
[Full article] from Greatist
Can Food Really Protect Me from the Sun?
The same components that protect plants from the sun—carotenoids and flavonoids—can help humans ward off sun damage. When ingested, these micronutrients act as antioxidants that protect the skin. Molecules in foods containing carotenoids and flavonoids like tomatoes, carrots, and even dark chocolate, may also absorb UV light to protect skin cells from damage.
[Full article] from Outside Magazine
Words to the Wise
In conceiving, designing and producing our antioxidants-rich food products, we conduct a significant amount of ongoing research of publically available medical literature related to skin health and how it relates to sun exposure. We make all this information available on our website, in both summary and detailed versions.
Help yourself to this information, and if you have any questions or concerns, don’t hesitate to let us know. We started Waxhead to help people just like us, who are hungry for good faith truth about how the foods we eat and the things we do can either help or hurt our bodies.
And a word to the wise. Waxhead Bars are a useful skin-defense tool, but they’re not a panacea. Healthy skin, just like a healthy body, isn’t achieved by any one action. It comes from doing what you can, and all you can, in an intelligent, wise way.
So when using our products, don’t be foolish. When you’re in the sun, continue to cover up with proper clothing and use sunscreen with sufficient SPF based on your exposure time. And rely on qualified health professionals to guide your skin-care efforts. Be smart.
Please know that Waxhead products are not intended to diagnose, treat, cure, or prevent any medical disorder or disease. Our claims and statements have not been evaluated by the Food and Drug Administration. If you have any questions relating to specific health concerns, consult a qualified healthcare professional.
The information on this website is intended for your general information, and is not a substitute for medical advice from such professionals. Do not disregard qualified medical advice or postpone consultation with your healthcare provider because of information you read on this website. Whew.